Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the Endothelium
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.07.020
Abstract: SUMMARY Consistent daylight oscillations and abundant oxygen availability are fundamental to human health. Here, we investigate the intersection between light-sensing (Period 2 [PER2]) and oxygen-sensing (hypoxia-inducible factor [HIF1A]) pathways in cellular adaptation to myocardial ischemia.… read more here.
Keywords: mediated circadian; per2; light mediated; myocardial ischemia ... See more keywords
Design and analysis of intense light beam by microlens engraved optical fiber
Sign Up to like & getrecommendations! Published in 2019 at "Optical Engineering"
DOI: 10.1117/1.oe.58.2.027114
Abstract: Abstract. We demonstrate the design and simulation of intense light beam (ILB) achieved by concave microlens engraved lenticular fibers. Both single and multiple microlenses of spherical and elliptical shapes have been incorporated just inside the… read more here.
Keywords: beam; intense light; microlens engraved; light intensity ... See more keywords
Intense light as anticoagulant therapy in humans
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0244792
Abstract: Blood coagulation is central to myocardial ischemia and reperfusion (IR) injury. Studies on the light elicited circadian rhythm protein Period 2 (PER2) using whole body Per2-/- mice found deficient platelet function and reduced clotting which… read more here.
Keywords: per2; intense light; mice; therapy ... See more keywords