Reduced Intensity Conditioning for Allogeneic Hematopoietic Cell Transplantation Utilizing Cladribine and Melphalan
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.786
Abstract: Introduction Reduced intensity conditioning (RIC) allogeneic hematopoietic cell transplantation (HCT) has been shown to be successful; however, the ideal RIC regimen is not known. In this study, we report the pooled results of three separate… read more here.
Keywords: reduced intensity; gvhd; transplantation; cell ... See more keywords
Safety Profile and Efficacy of Cidofovir for Adenovirus in Pediatric Stem Cell Transplant Recipients Following Reduced-Intensity Conditioning
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2019.12.311
Abstract: Background Adenovirus (ADV) infection remains a significant cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation (allo-HSCT), particularly in the pediatric population. Pre-emptive monitoring by polymerase chain reaction (PCR) assay for ADV viremia… read more here.
Keywords: intensity conditioning; treatment; cdv; pcr ... See more keywords
Lentiviral globin gene therapy with reduced-intensity conditioning in adults with β-thalassemia: a phase 1 trial
Sign Up to like & getrecommendations! Published in 2022 at "Nature Medicine"
DOI: 10.1038/s41591-021-01554-9
Abstract: β-Thalassemias are inherited anemias that are caused by the absent or insufficient production of the β chain of hemoglobin. Here we report 6–8-year follow-up of four adult patients with transfusion-dependent β-thalassemia who were infused with… read more here.
Keywords: reduced intensity; intensity conditioning; lentiviral globin; globin ... See more keywords
Successful Umbilical Cord Blood Transplantation With Reduced-intensity Conditioning for Acute Myeloid Leukemia in a Child With Shwachman-Diamond Syndrome.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000001773
Abstract: Outcomes of patients with Shwachman-Diamond syndrome (SDS) who developed myeloid malignancies are poor because of refractory disease and high hematopoietic stem cell transplantation-related mortality. We herein report a case of a 7-year-old girl with SDS… read more here.
Keywords: myeloid leukemia; acute myeloid; reduced intensity; transplantation ... See more keywords
ALL-RIC trial protocol: a comparison of reduced dose total body irradiation (TBI) and cyclophosphamide with fludarabine and melphalan reduced intensity conditioning in adults with acute lymphoblastic leukaemia (ALL) in complete remission.
Sign Up to like & getrecommendations! Published in 2023 at "BMJ open"
DOI: 10.1136/bmjopen-2022-067790
Abstract: Introduction The usage of a T-cell depleted, reduced intensity conditioning (RIC) approach to haematopoietic cell transplantation (HCT) in adult patients with acute lymphoblastic leukaemia (ALL) over 40 years of age and in first complete remission… read more here.
Keywords: intensity conditioning; conditioning; trial; reduced intensity ... See more keywords
Reduced intensity conditioning for acute myeloid leukemia using melphalan- vs busulfan-based regimens: a CIBMTR report.
Sign Up to like & getrecommendations! Published in 2020 at "Blood advances"
DOI: 10.1182/bloodadvances.2019001266
Abstract: There is a lack of large comparative study on the outcomes of reduced intensity conditioning (RIC) in acute myeloid leukemia (AML) transplantation using fludarabine/busulfan (FB) and fludarabine/melphalan (FM) regimens. Adult AML patients from Center for… read more here.
Keywords: intensity conditioning; myeloid leukemia; reduced intensity; acute myeloid ... See more keywords
Comparison of myeloablative vs reduced intensity conditioning regimens in stem cell transplantations for acute myeloid leukemia.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e18518
Abstract: e18518Background: The development of reduced intensity conditioning (RIC) regimens enabled allogeneic hematopoietic stem cell transplantations (allo-HSCT) also for patients who had contraindication... read more here.
Keywords: stem cell; intensity conditioning; reduced intensity; cell transplantations ... See more keywords
Bortezomib-based immunosuppression after reduced-intensity conditioning hematopoietic stem cell transplantation: randomized phase II results
Sign Up to like & getrecommendations! Published in 2018 at "Haematologica"
DOI: 10.3324/haematol.2017.176859
Abstract: Aprior phase I/II trial of bortezomib/tacrolimus/methotrexate prophylaxis after human leukocyte antigen (HLA)-mismatched reduced intensity conditioning allogeneic hematopoietic stem cell transplantation documented low acute graft-versus-host disease incidence, with promising overall and progression-free survival. We performed an… read more here.
Keywords: intensity conditioning; versus host; reduced intensity; versus ... See more keywords