Association Between Intensity of Statin Therapy and Mortality in Patients With Atherosclerotic Cardiovascular Disease
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DOI: 10.1001/jamacardio.2016.4052
Abstract: Importance High-intensity statin therapy is recommended for the secondary prevention of atherosclerotic cardiovascular disease (ASCVD). Nevertheless, statin therapy in general, and high-intensity statin therapy in particular, is underused in patients with established ASCVD. Objective To… read more here.
Keywords: statin therapy; high intensity; intensity statin; intensity ... See more keywords
Trends in Use of High-Intensity Statin Therapy After Myocardial Infarction, 2011 to 2014.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2017.03.585
Abstract: BACKGROUND Data prior to 2011 suggest that a low percentage of patients hospitalized for acute coronary syndromes filled high-intensity statin prescriptions upon discharge. Black-box warnings, generic availability of atorvastatin, and updated guidelines may have resulted… read more here.
Keywords: 2011 2014; intensity statin; intensity; high intensity ... See more keywords
EFFECT OF CHRONIC KIDNEY DISEASE ON DIFFERENT INTENSITY STATIN UTILIZATION IN PATIENTS WITH CORONARY ARTERY DISEASE: A SINGLE TERTIARY CENTER EXPERIENCE
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(18)30713-7
Abstract: High-intensity statin use is indicated for all patients with coronary artery disease (CAD). It is unclear whether there are lower rates of high-intensity statin use in patients with chronic kidney disease (CKD) due to concerns… read more here.
Keywords: coronary artery; patients coronary; intensity statin; disease ... See more keywords
REGIONAL VARIATION IN INTENSITY OF STATIN PRESCRIPTION
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(19)30699-0
Abstract: The 9 states of southeastern USA (SE states) are known to have worse atherosclerotic cardiovascular disease (ASCVD) outcomes compared to the national average. High intensity statins(HIS) are recommended for patients at high vascular risk. We… read more here.
Keywords: statin prescription; intensity; intensity statin; variation intensity ... See more keywords
Moderate-intensity statin with ezetimibe vs. high-intensity statin in patients with diabetes and atherosclerotic cardiovascular disease in the RACING trial.
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DOI: 10.1093/eurheartj/ehac709
Abstract: AIMS This study evaluated the effect of moderate-intensity statin with ezetimibe combination therapy vs. high-intensity statin monotherapy among patients with diabetes mellitus (DM) and atherosclerotic cardiovascular disease (ASCVD). METHODS AND RESULTS This was a pre-specified,… read more here.
Keywords: trial; therapy; high intensity; intensity ... See more keywords
Comparative effect of statin intensity between prediabetes and type 2 diabetes mellitus after implanting newer-generation drug-eluting stents in Korean acute myocardial infarction patients: a retrospective observational study
Sign Up to like & getrecommendations! Published in 2021 at "BMC Cardiovascular Disorders"
DOI: 10.1186/s12872-021-02198-w
Abstract: Background Comparative studies regarding the long-term clinical outcomes of statin intensity between acute myocardial infarction (AMI) patients with prediabetes and those with type 2 diabetes mellitus (T2DM), after successful implantation of newer-generation drug-eluting stents (DES)… read more here.
Keywords: intensity statin; low moderate; statin; intensity ... See more keywords
High-intensity statin therapy yields better outcomes in acute coronary syndrome patients: a meta-analysis involving 26,497 patients
Sign Up to like & getrecommendations! Published in 2020 at "Lipids in Health and Disease"
DOI: 10.1186/s12944-020-01369-6
Abstract: Background Whether high-intensity statin treatment provides more clinical benefits compared with standard statin regimens in acute coronary syndrome (ACS) patients remains controversial. This meta-analysis aimed to comparatively assess high-intensity and standard statin regimens for efficacy… read more here.
Keywords: statin therapy; high intensity; intensity statin; intensity ... See more keywords
Comparative safety and efficacy of low- or moderate-intensity statin plus ezetimibe combination therapy and high-intensity statin monotherapy: A meta-analysis of randomized controlled studies
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0264437
Abstract: Statin is highly recommended for dyslipidemia to prevent atherosclerosis-related cardiovascular diseases and death. The aim of this study was to compare the efficacies and safeties of low/moderate-intensity statin plus ezetimibe combination therapy vs. high-intensity statin… read more here.
Keywords: intensity statin; low moderate; moderate intensity; statin ... See more keywords
Effect of Ezetimibe Added to High-Intensity Statin Therapy on Low-Density Lipoprotein Cholesterol Levels: A Meta-Analysis
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DOI: 10.14740/cr1224
Abstract: Background Adding ezetimibe to high-intensity statin therapy is used for additional lowering of low-density lipoprotein cholesterol (LDL-C); however, there are little data on the efficacy of ezetimibe when combined with a high-intensity statin. A meta-analysis… read more here.
Keywords: statin therapy; high intensity; intensity statin;
Effects of Evolocumab Added to Moderate-Intensity Statin Therapy in Chinese Patients With Acute Coronary Syndrome: The EMSIACS Trial Study Protocol
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.750872
Abstract: Background: Several studies have demonstrated that using a higher dose of statin can easily induce liver injury and myopathy. Low-density lipoprotein cholesterol (LDL-C) is a well-established modifiable risk factor for cardiovascular disease; however, the large… read more here.
Keywords: moderate intensity; intensity statin; chinese patients; evolocumab added ... See more keywords