Intensive insulin therapy combined with metformin is associated with reduction in both glucose variability and nocturnal hypoglycaemia in patients with type 2 diabetes
Sign Up to like & getrecommendations! Published in 2017 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.2913
Abstract: The effect on glucose variability in patients with intensive insulin therapy has not been fully understood. This observational study investigated the different glucose variability and hypoglycaemia patterns in type 2 diabetes patients treated with continuous… read more here.
Keywords: intensive insulin; insulin therapy; variability; glucose variability ... See more keywords
Modulation of gut microbiota contributes to effects of intensive insulin therapy on intestinal morphological alteration in high-fat-diet-treated mice
Sign Up to like & getrecommendations! Published in 2019 at "Acta Diabetologica"
DOI: 10.1007/s00592-019-01436-0
Abstract: Aims Disturbance of intestinal homeostasis promotes the development of type 2 diabetes. Although intensive insulin therapy has been shown to promote extended glycemic remission in newly diagnosed type 2 diabetic patients through multiple mechanisms, its… read more here.
Keywords: effects intensive; intensive insulin; insulin therapy; gut microbiota ... See more keywords
Enhancing Resources for Healthcare Professionals Caring for People on Intensive Insulin Therapy: Summary from a National Workshop.
Sign Up to like & getrecommendations! Published in 2020 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2020.108169
Abstract: In June 2019, the Leona M. and Harry B. Helmsley Charitable Trust and JDRF International (JDRF) co-sponsored the Healthcare Professional Resource Workshop in San Francisco, California. The workshop convened stakeholders in the diabetes field in… read more here.
Keywords: workshop; intensive insulin; caring people; insulin therapy ... See more keywords
Evaluating the role of time in range as a glycemic target during short‐term intensive insulin therapy in patients with newly diagnosed type 2 diabetes
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Diabetes"
DOI: 10.1111/1753-0407.13355
Abstract: Tight glycemic control during short‐term intensive insulin therapy (SIIT) is critical for inducing diabetes remission in patients with newly diagnosed type 2 diabetes (T2D). This work aimed to investigate the role of time in range… read more here.
Keywords: term intensive; patients newly; newly diagnosed; insulin therapy ... See more keywords
Short‐term intensive insulin as induction and maintenance therapy for the preservation of beta‐cell function in early type 2 diabetes (RESET‐IT Main): A 2‐year randomized controlled trial
Sign Up to like & getrecommendations! Published in 2021 at "Diabetes"
DOI: 10.1111/dom.14421
Abstract: To test the hypothesis that the addition of periodic courses of short‐term intensive insulin therapy (IIT) could enhance the effect of metformin (MET) maintenance therapy on preservation of beta‐cell function following induction IIT. read more here.
Keywords: maintenance therapy; intensive insulin; therapy; short term ... See more keywords
Efficacy and safety of basal‐first titration order in individuals with type 2 diabetes receiving short‐term intensive insulin therapy: An exploratory analysis of BEYOND V
Sign Up to like & getrecommendations! Published in 2023 at "Diabetes"
DOI: 10.1111/dom.14970
Abstract: To present the results of an exploratory analysis of the BEYOND V study in which Chinese individuals with uncontrolled type 2 diabetes (T2D) received short‐term intensive insulin therapy (SIIT) during study run‐in (prior to randomization)… read more here.
Keywords: term intensive; exploratory analysis; type diabetes; intensive insulin ... See more keywords
Development and Validation of a Hypoglycemia Risk Model for Intensive Insulin Therapy in Patients with Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Diabetes Research"
DOI: 10.1155/2020/7292108
Abstract: Aims To develop a simple hypoglycemic prediction model to evaluate the risk of hypoglycemia during hospitalization in patients with type 2 diabetes treated with intensive insulin therapy. Methods We performed a cross-sectional chart review study… read more here.
Keywords: patients type; intensive insulin; hypoglycemia; model ... See more keywords
Technological Support to Intensive Insulin Therapy by a Novel Smartphone Application in Young Adults With Type 1 Diabetes: One Center’s Experience
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Diabetes Science and Technology"
DOI: 10.1177/1932296818803937
Abstract: In our Diabetes Centre at Sapienza University of Rome, Italy, we have been exploring the potential benefits of using technology in diabetes care, with a particular focus on T1DM patients receiving flexible intensive insulin therapy… read more here.
Keywords: insulin; intensive insulin; insulin therapy; t1dm ... See more keywords
Socioeconomic disparities in access to intensive insulin regimens for adults with type 1 diabetes: a qualitative study of patient and healthcare professional perspectives
Sign Up to like & getrecommendations! Published in 2019 at "International Journal for Equity in Health"
DOI: 10.1186/s12939-019-1061-8
Abstract: BackgroundType 1 diabetes is a complex chronic condition which requires lifelong treatment with insulin. Health outcomes are dependent on ability to self-manage the condition. Socioeconomic inequalities have been demonstrated in access to treatment and health… read more here.
Keywords: insulin; healthcare; intensive insulin; access intensive ... See more keywords
Intensive insulin therapy versus plasmapheresis in the management of hypertriglyceridemia-induced acute pancreatitis (Bi-TPAI trial): study protocol for a randomized controlled trial
Sign Up to like & getrecommendations! Published in 2019 at "Trials"
DOI: 10.1186/s13063-019-3498-x
Abstract: BackgroundIt is widely agreed that triglyceride (TG)-lowering therapy is imperative in early hypertriglyceridemia-induced acute pancreatitis (HTG-AP). Intravenous insulin with or without heparin, and plasmapheresis are available regimens. However, there is no consensus on first-line therapy.Methods/designThe… read more here.
Keywords: trial; tpai trial; intensive insulin; therapy ... See more keywords
The effect of short-term intensive insulin therapy in newly-diagnosed Type-2 diabetic patients
Sign Up to like & getrecommendations! Published in 2021 at "Pakistan Journal of Medical Sciences"
DOI: 10.12669/pjms.37.7.4013
Abstract: Objectives: We aimed to determine the effect of short-term intensive insulin therapy (SIIT) on long-term glycemic control in newly-diagnosed Type-2 diabetes mellitus (nT2DM) patients. Methods: In this retrospectively study conducted at Sakarya University Medical Faculty… read more here.
Keywords: insulin therapy; insulin; intensive insulin; term ... See more keywords