Intention‐to‐treat survival benefit in liver transplantation: Comments on Lai et al.
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DOI: 10.1002/hep.29755
Abstract: model selections is no different, and effect estimates are largely unchanged. We also agree with Ridola and Riggio that the presence of minimal HE is predictive of incident overt HE. However, minimal HE is not… read more here.
Keywords: survival benefit; benefit liver; intention treat; liver transplantation ... See more keywords
Intention to treat versus modified intention-to-treat analysis in B-cell maturation antigen and CD19 chimeric antigen receptor trials: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of cancer"
DOI: 10.1016/j.ejca.2021.07.036
Abstract: INTRODUCTION Chimeric antigen receptor T-cell therapy (CART) has revolutionised treatment of haematological malignancies; however, current reporting uses a modified intention-to-treat analysis (mITT) which over-estimates efficacy. We assessed what proportion of CD19 and B-cell maturation antigen… read more here.
Keywords: cart; cd19; antigen; intention treat ... See more keywords
OP52 Use Of Intention To Treat And Magnitude Of Treatment Effects
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DOI: 10.1017/s0266462319001168
Abstract: Introduction Intention to treat (ITT) is a gold standard strategy to analyze the results of randomized controlled trials (RCTs). ITT analysis has been considered a methodological indicator of the quality of clinical trials. The extent… read more here.
Keywords: treatment; intention; use intention; intention treat ... See more keywords
Influence of allocation concealment and intention-to-treat analysis on treatment effects of physical therapy interventions in low back pain randomised controlled trials: a protocol of a meta-epidemiological study
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DOI: 10.1136/bmjopen-2017-017301
Abstract: Introduction Meta-epidemiological studies examining the influence of methodological characteristics, such as allocation concealment and intention-to-treat analysis have been performed in a large number of healthcare areas. However, there are no studies investigating these characteristics in… read more here.
Keywords: allocation concealment; analysis; treat analysis; intention treat ... See more keywords
Using modified intention-to-treat as a principal stratum estimator for failure to initiate treatment.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical trials"
DOI: 10.1177/17407745231160074
Abstract: Background: A common intercurrent event affecting many trials is when some participants do not begin their assigned treatment. For example, in a double-blind drug trial, some participants may not receive any dose of study medication.… read more here.
Keywords: intention treat; treatment; estimator; modified intention ... See more keywords