Plasma Cell Fate Is Orchestrated by Elaborate Changes in Genome Compartmentalization and Inter-chromosomal Hubs.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.107876
Abstract: Summary The transition from the follicular B to the plasma cell stage is associated with large-scale changes in cell morphology. Here, we examine whether plasma cell development is also associated with changes in nuclear architecture. We… read more here.
Keywords: chromosomal hubs; plasma cell; inter chromosomal; cell ... See more keywords
Inter-chromosomal Contact Properties in Live-Cell Imaging and in Hi-C.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.02.007
Abstract: Imaging (fluorescence in situ hybridization [FISH]) and genome-wide chromosome conformation capture (Hi-C) are two major approaches to the study of higher-order genome organization in the nucleus. Intra-chromosomal and inter-chromosomal interactions (referred to as non-homologous chromosomal contacts… read more here.
Keywords: spatiotemporal properties; cell imaging; live cell; cell ... See more keywords
57. ADDITIONAL DATA FOR CONTROVERSIAL INTER-CHROMOSOMAL EFFECT SUSCEPTIBILITY IN PGT-SR PATIENTS
Sign Up to like & getrecommendations! Published in 2019 at "Reproductive BioMedicine Online"
DOI: 10.1016/j.rbmo.2019.04.110
Abstract: Introduction NGS based translocation testing has been widely used as the possibility of detecting other chromosomal aneuploidies. Some studies claimed that balanced translocation carriers may have an increased risk for aneuploidies unrelated to translocation due… read more here.
Keywords: aneuploidy; inter chromosomal; translocation; pgt ... See more keywords
Disclosing complex mutational dynamics at a Y chromosome palindrome evolving through intra- and inter-chromosomal gene conversion.
Sign Up to like & getrecommendations! Published in 2022 at "Human molecular genetics"
DOI: 10.1093/hmg/ddac144
Abstract: The human MSY ampliconic region is mainly composed of large duplicated sequences that are organized in eight palindromes (termed P1-P8), and may undergo arm-to-arm gene conversion. Although the importance of these elements is widely recognised,… read more here.
Keywords: chromosomal gene; gene conversion; intra inter; gene ... See more keywords
Probabilistic establishment of speckle-associated inter-chromosomal interactions.
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic acids research"
DOI: 10.1093/nar/gkad211
Abstract: Inter-chromosomal interactions play a crucial role in genome organization, yet the organizational principles remain elusive. Here, we introduce a novel computational method to systematically characterize inter-chromosomal interactions using in situ Hi-C results from various cell… read more here.
Keywords: inter; speckle associated; associated inter; chromosomal interactions ... See more keywords
Patterns of Inter-Chromosomal Gene Conversion on the Male-Specific Region of the Human Y Chromosome
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2017.00054
Abstract: The male-specific region of the human Y chromosome (MSY) is characterized by the lack of meiotic recombination and it has long been considered an evolutionary independent region of the human genome. In recent years, however,… read more here.
Keywords: region human; gene conversion; chromosomal gene; inter chromosomal ... See more keywords