MAPK-interacting kinase 1 (Mnk1) regulates platelet production, activation, and thrombosis.
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DOI: 10.1182/blood.2022015568
Abstract: The MAPK-interacting kinase (Mnk) family includes Mnk1 and Mnk2, which are phosphorylated and activated in response to extracellular stimuli. Mnk1 contributes to cellular responses by regulating mRNA translation and mRNA translation influences platelet production and… read more here.
Keywords: mnk1 regulates; mnk1; interacting kinase; mapk interacting ... See more keywords
Feasibility of Targeting Traf2-and-Nck-Interacting Kinase in Synovial Sarcoma
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DOI: 10.3390/cancers12051258
Abstract: Background: The treatment of patients with metastatic synovial sarcoma is still challenging, and the development of new molecular therapeutics is desirable. Dysregulation of Wnt signaling has been implicated in synovial sarcoma. Traf2-and-Nck-interacting kinase (TNIK) is… read more here.
Keywords: sarcoma; tnik; nck interacting; synovial sarcoma ... See more keywords