Interacting motif networks located in hotspots associated with RNA release are conserved in Enterovirus capsids
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12663
Abstract: Enteroviruses are responsible for a multitude of human diseases. Expansion of the virus capsid is associated with a cascade of conformational changes that allow the subsequent release of RNA. For the first time, this study… read more here.
Keywords: interacting motif; rna release; networks located; motif networks ... See more keywords
Dimerization of a ubiquitin variant leads to high affinity interactions with a ubiquitin interacting motif
Sign Up to like & getrecommendations! Published in 2019 at "Protein Science"
DOI: 10.1002/pro.3593
Abstract: We previously described structural and functional characterization of the first ubiquitin variant (UbV), UbV.v27.1, engineered by phage display to bind with high affinity to a specific ubiquitin interacting motif (UIM). We identified two substitutions relative… read more here.
Keywords: interacting motif; high affinity; affinity; dimerization ... See more keywords