Functional hierarchy of PCNA‐interacting motifs in DNA processing enzymes
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DOI: 10.1002/bies.202300020
Abstract: Numerous eukaryotic DNA processing enzymes, such as DNA polymerases and ligases, bind the processivity factor PCNA, which acts as a platform to recruit and regulate the binding of enzymes to their DNA substrate. Multiple PCNA‐interacting… read more here.
Keywords: pcna; dna processing; dna; pcna interacting ... See more keywords
Panel of Engineered Ubiquitin Variants Targeting the Family of Human Ubiquitin Interacting Motifs.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.2c00089
Abstract: Ubiquitin (Ub)-binding domains embedded in intracellular proteins act as readers of the complex Ub code and contribute to regulation of numerous eukaryotic processes. Ub-interacting motifs (UIMs) are short α-helical modular recognition elements whose role in… read more here.
Keywords: variants targeting; panel engineered; interacting motifs; ubiquitin variants ... See more keywords