BioID: A Proximity-Dependent Labeling Approach in Proteomics Study.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8814-3_10
Abstract: Biological activities are mainly executed by proteins and in most of the occasions these activities are accomplished by protein complexes or through protein-protein interactions (PPI). So it is critical to reveal how the protein complexes… read more here.
Keywords: protein; target protein; interacting partners; dependent labeling ... See more keywords
Physiological tau interactome in brain and its link to tauopathies.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.0c00137
Abstract: Alzheimer's disease (AD) and most of the other tauopathies are incurable neurodegenerative diseases with unpleasant symptoms and consequences. The common hallmark of all these diseases is tau pathology, but its connection with disease progress has… read more here.
Keywords: tau interacting; tau; physiological tau; tau pathology ... See more keywords
Protein prediction models support widespread post-transcriptional regulation of protein abundance by interacting partners
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Computational Biology"
DOI: 10.1101/2022.03.14.484316
Abstract: Protein and mRNA levels correlate only moderately. The availability of proteogenomics data sets with protein and transcript measurements from matching samples is providing new opportunities to assess the degree to which protein levels in a… read more here.
Keywords: protein abundance; abundance; prediction models; interacting partners ... See more keywords
New Interacting Partners of BLADE-ON-PETIOLE in Regulation of Plant Development
Sign Up to like & getrecommendations! Published in 2019 at "Plant Physiology"
DOI: 10.1104/pp.19.00459
Abstract: Organ boundaries are junctions that separate initiating lateral organs from the meristem or other plant parts. Cells at the boundary often exhibit slow growth rates and morphology distinct from that of the surrounding cells, and… read more here.
Keywords: blade petiole; plant; partners blade; interacting partners ... See more keywords
Intracellular β2 integrin (CD11/CD18) interacting partners in neutrophil trafficking
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Clinical Investigation"
DOI: 10.1111/eci.12966
Abstract: Neutrophil recruitment during acute inflammation critically depends on the spatial and temporal regulation of β2 integrins (CD11/CD18). This regulation occurs by inside‐out and outside‐in signalling via interaction of cytoplasmic proteins with the intracellular domains of… read more here.
Keywords: partners neutrophil; cd18 interacting; integrin cd11; cd11 cd18 ... See more keywords
PRMT5 Interacting Partners and Substrates in Oligodendrocyte Lineage Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.820226
Abstract: The protein arginine methyl transferase PRMT5 is an enzyme expressed in oligodendrocyte lineage cells and responsible for the symmetric methylation of arginine residues on histone tails. Previous work from our laboratory identified PRMT5 as critical… read more here.
Keywords: oligodendrocyte lineage; prmt5; interacting partners; lineage cells ... See more keywords
Group I Metabotropic Glutamate Receptors and Interacting Partners: An Update
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020840
Abstract: Group I metabotropic glutamate (mGlu) receptors (mGlu1/5 subtypes) are G protein-coupled receptors and are broadly expressed in the mammalian brain. These receptors play key roles in the modulation of normal glutamatergic transmission and synaptic plasticity,… read more here.
Keywords: group; metabotropic glutamate; interacting partners; group metabotropic ... See more keywords
Proximity Labeling to Identify β-Arrestin1 Binding Partners Downstream of Ligand-Activated G Protein-Coupled Receptors
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043285
Abstract: β-arrestins are multifaceted adaptor proteins that regulate various aspects of G protein-coupled receptor (GPCR) signaling. β-arrestins are recruited to agonist-activated and phosphorylated GPCRs at the plasma membrane, thereby preventing G protein coupling, while also targeting… read more here.
Keywords: proximity; arr1 apex; interacting partners; proximity labeling ... See more keywords