Thermodynamic signature of indoloquinolines interacting with G-quadruplexes: Impact of ligand side chain.
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DOI: 10.1016/j.biochi.2018.11.015
Abstract: Binding of indoloquinolines with different aliphatic side chains to a parallel G-quadruplex derived from the MYC promoter sequence was characterized by optical and calorimetric measurements. ITC experiments performed at different temperatures enabled the determination of… read more here.
Keywords: thermodynamic signature; ligand side; signature indoloquinolines; interacting quadruplexes ... See more keywords