Decay of Piwi-Interacting RNAs in Human Cells Is Primarily Mediated by 5' to 3' Exoribonucleases.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.2c00007
Abstract: Piwi-interacting RNAs (piRNAs) are a group of small noncoding RNA molecules that regulate the activity of transposons and control gene expression. The cellular concentration of RNAs is generally maintained by their rates of biogenesis and… read more here.
Keywords: piwi interacting; rnas human; interacting rnas; degradation ... See more keywords
Decoding the 5′ nucleotide bias of PIWI-interacting RNAs
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-08803-z
Abstract: PIWI-interacting RNAs (piRNAs) are at the center of a small RNA-based immune system that defends genomes against the deleterious action of mobile genetic elements (transposons). PiRNAs are highly variable in sequence with extensive targeting potential.… read more here.
Keywords: piwi interacting; bias piwi; piwi; nucleotide bias ... See more keywords
An introduction to PIWI-interacting RNAs (piRNAs) in the context of metazoan small RNA silencing pathways
Sign Up to like & getrecommendations! Published in 2022 at "RNA Biology"
DOI: 10.1080/15476286.2022.2132359
Abstract: ABSTRACT PIWI proteins and their associated PIWI-interacting RNAs (piRNAs) constitute a small RNA-based adaptive immune system that restricts the deleterious activity of mobile genetic elements to protect genome integrity. Self/nonself discrimination is at the very… read more here.
Keywords: piwi interacting; rna; rnas pirnas; interacting rnas ... See more keywords
PIWI-interacting RNAs in human diseases: databases and computational models
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac217
Abstract: PIWI-interacting RNAs (piRNAs) are short 21-35 nucleotide molecules that comprise the largest class of non-coding RNAs and found in a large diversity of species including yeast, worms, flies, plants and mammals including humans. The most… read more here.
Keywords: piwi interacting; computational models; human diseases; databases computational ... See more keywords
Prediction of Piwi-Interacting RNAs and Their Functions via Convolutional Neural Network
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DOI: 10.1109/access.2021.3070083
Abstract: In eukaryotic cells, Piwi-interacting RNAs (piRNAs) are the type of short chain non-coding RNA molecules, which interconnect with PIWI proteins. It performs various cellular and genetic functions such as gene-specific protein translation, expression regulation, maintenance,… read more here.
Keywords: neural network; piwi interacting; interacting rnas; convolutional neural ... See more keywords
PIWI-Interacting RNAs (piRNAs): Promising Applications as Emerging Biomarkers for Digestive System Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.848105
Abstract: PIWI-interacting RNAs (piRNAs) are a novel type of small non-coding RNAs (sncRNAs), which are 26–31 nucleotides in length and bind to PIWI proteins. Although piRNAs were originally discovered in germline cells and are thought to… read more here.
Keywords: cancer; pirnas promising; interacting rnas; piwi interacting ... See more keywords
PIWI-interacting RNAs in cancer: Biogenesis, function, and clinical significance
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.965684
Abstract: PIWI-interacting RNAs (piRNAs) are a less-studied class of small non-coding RNAs approximately 24–31 nucleotides in length. They express in germline and somatic cells and form complexes with PIWI proteins to exert regulatory effects. New studies… read more here.
Keywords: piwi interacting; biogenesis function; rnas cancer; interacting rnas ... See more keywords