The interaction between autophagy and neuroinflammation in major depressive disorder: from pathophysiology to therapeutic implications.
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacological research"
DOI: 10.1016/j.phrs.2021.105586
Abstract: The past decade has revealed neuroinflammation as an important mechanism of major depressive disorder (MDD). Nod-like receptors family pyrin domain containing 3 (NLRP3) inflammasome is the key regulator interleukin-1β (IL-1β) maturation, whose activation has been… read more here.
Keywords: interaction autophagy; depressive disorder; neuroinflammation; major depressive ... See more keywords
Interaction between autophagy and the NLRP3 inflammasome in Alzheimer’s and Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.1018848
Abstract: Autophagy degrades phagocytosed damaged organelles, misfolded proteins, and various pathogens through lysosomes as an essential way to maintain cellular homeostasis. Autophagy is a tightly regulated cellular self-degradation process that plays a crucial role in maintaining… read more here.
Keywords: autophagy nlrp3; disease; nlrp3 inflammasome; interaction autophagy ... See more keywords