Identification of interaction domains in the pseudorabies virus ribonucleotide reductase large and small subunits.
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2020.108740
Abstract: Alphaherpesviral ribonucleotide reductase (RNR) is composed of large (pUL39, RR1) and small (pUL40, RR2) subunits. This enzyme can catalyze conversion of ribonucleotide to deoxynucleotide diphosphates that are further phosphorylated into deoxynucleotide triphosphate (dNTPs). The dNTPs… read more here.
Keywords: interaction domains; pul39 pul40; rnr; interaction ... See more keywords
Electrostatically Driven Guanidinium Interaction Domains that Control Hydrogel-Mediated Protein Delivery In Vivo
Sign Up to like & getrecommendations! Published in 2019 at "ACS Central Science"
DOI: 10.1021/acscentsci.9b00501
Abstract: Protein biologics are an important class of drugs, but the necessity for frequent parenteral administration is a major limitation. Drug-delivery materials offer a potential solution, but protein-material adsorption can cause denaturation, which reduces their effectiveness.… read more here.
Keywords: protein; interaction domains; protein delivery; delivery ... See more keywords