Factor VIIa interaction with EPCR modulates the hemostatic effect of rFVIIa in hemophilia therapy: Mode of its action.
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DOI: 10.1182/bloodadvances.2016004143
Abstract: Recent studies established that clotting factor VIIa (FVIIa) binds endothelial cell protein C receptor (EPCR). It has been speculated that FVIIa interaction with EPCR might augment the hemostatic effect of rFVIIa in therapeutic conditions. The… read more here.
Keywords: epcr; hemostatic effect; effect rfviia; interaction epcr ... See more keywords