Facilitating crRNA Design by Integrating DNA Interaction Features of CRISPR‐Cas12a System
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DOI: 10.1002/advs.202501269
Abstract: The CRISPR‐Cas12a system has gained significant attention as a rapid nucleic acid diagnostic tool due to its crRNA‐guided trans‐cleavage activity. Accurately predicting the activity of different targets is significant to facilitate the crRNA availability but… read more here.
Keywords: interaction features; crispr cas12a; cas12a; cas12a system ... See more keywords
Interaction features for prediction of perceptual segmentation: Effects of musicianship and experimental task
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DOI: 10.1080/09298215.2016.1230137
Abstract: As music unfolds in time, structure is recognised and understood by listeners, regardless of their level of musical expertise. A number of studies have found spectral and tonal changes to quite successfully model boundaries between… read more here.
Keywords: task; segmentation; time; interaction features ... See more keywords
A simple spatial extension to the extended connectivity interaction features for binding affinity prediction
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DOI: 10.1098/rsos.211745
Abstract: The representation of the protein-ligand complexes used in building machine learning models play an important role in the accuracy of binding affinity prediction. The Extended Connectivity Interaction Features (ECIF) is one such representation. We report… read more here.
Keywords: extended connectivity; binding affinity; affinity prediction; interaction features ... See more keywords