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Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-63306-4
Abstract: Genetic interactions are fundamental to the architecture of complex traits, yet the molecular mechanisms by which variant combinations influence cellular pathways remain poorly understood. Here, we answer the question of whether interactions between genetic variants…
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Keywords:
latent metabolic;
interaction genetic;
metabolic pathways;
variants activates ... See more keywords
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Published in 2022 at "BJU International"
DOI: 10.1111/bju.15880
Abstract: To investigate the association of polygenic risk score (PRS) and bladder cancer (BC) risk and whether this PRS can be offset by a healthy lifestyle.
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Keywords:
interaction genetic;
risk;
cancer risk;
bladder cancer ... See more keywords
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Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.917850
Abstract: Background LADA is a common form of diabetes described as a mix between type 1 and type 2 diabetes. Understanding of how genes and environmental factors interact in the development of LADA is central for…
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Keywords:
risk lada;
interaction genetic;
risk;
genetic susceptibility ... See more keywords