TAAR1-Dependent and -Independent Actions of Tyramine in Interaction With Glutamate Underlie Central Effects of Monoamine Oxidase Inhibition
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DOI: 10.1016/j.biopsych.2020.12.008
Abstract: BACKGROUND Monoamine oxidase inhibitors (MAOIs) exert therapeutic actions by elevating extracellular levels of monoamines in the brain. Irreversible MAOIs cause serious hypertensive crises owing to peripheral accumulation of tyramine, but the role of tyramine in… read more here.
Keywords: central effects; accumulation; interaction glutamate; monoamine oxidase ... See more keywords