Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study
Sign Up to like & getrecommendations! Published in 2017 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2016.09.022
Abstract: A recent study MacLeod et al. has shown that an interaction between variants at the LRRK2 and PARK16 loci influences risk of development of Parkinson's disease (PD). Our study examines the proposed interaction between LRRK2… read more here.
Keywords: risk; lrrk2 park16; interaction; study ... See more keywords
Allele-dependent interaction of LRRK2 and NOD2 in leprosy
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1011260
Abstract: Leprosy, caused by Mycobacterium leprae, rarely affects children younger than 5 years. Here, we studied a multiplex leprosy family that included monozygotic twins aged 22 months suffering from paucibacillary leprosy. Whole genome sequencing identified three… read more here.
Keywords: nod2 leprosy; lrrk2 nod2; dependent interaction; allele dependent ... See more keywords