A quantitative Streptococcus pyogenes–human protein–protein interaction map reveals localization of opsonizing antibodies
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-10583-5
Abstract: A fundamental challenge in medical microbiology is to characterize the dynamic protein–protein interaction networks formed at the host–pathogen interface. Here, we generate a quantitative interaction map between the significant human pathogen, Streptococcus pyogenes, and proteins… read more here.
Keywords: streptococcus pyogenes; map; protein protein; interaction ... See more keywords
Defining a microRNA‐mRNA interaction map for calcineurin inhibitor induced nephrotoxicity
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DOI: 10.1111/ajt.14503
Abstract: Calcineurin inhibitors induce nephrotoxicity through poorly understood mechanisms thereby limiting their use in transplantation and other diseases. Here we define a microRNA (miRNA)‐messenger RNA (mRNA) interaction map that facilitates exploration into the role of miRNAs… read more here.
Keywords: mrna interaction; interaction map; calcineurin; induced nephrotoxicity ... See more keywords
Abstract PR07: Identifying factors mediating response and resistance to chemotherapy through a chemical-genetic interaction map
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Cancer Research"
DOI: 10.1158/1557-3125.dnarepair16-pr07
Abstract: Nearly every cancer patient, especially those with highly lethal and aggressive tumor types, is treated with cytotoxic chemotherapy. Currently, the selection of chemotherapy is based on average responses over a large number of patients. This… read more here.
Keywords: response; chemical genetic; map; genetic interaction ... See more keywords