Active Interaction Mapping Reveals the Hierarchical Organization of Autophagy.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular cell"
DOI: 10.1016/j.molcel.2016.12.024
Abstract: We have developed a general progressive procedure, Active Interaction Mapping, to guide assembly of the hierarchy of functions encoding any biological system. Using this process, we assemble an ontology of functions comprising autophagy, a central recycling… read more here.
Keywords: mapping reveals; interaction mapping; active interaction; ontology ... See more keywords
Genetic interaction mapping with microfluidic-based single cell sequencing
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0171302
Abstract: Genetic interaction mapping is useful for understanding the molecular basis of cellular decision making, but elucidating interactions genome-wide is challenging due to the massive number of gene combinations that must be tested. Here, we demonstrate… read more here.
Keywords: single cell; microfluidic based; genetic interaction; interaction ... See more keywords