Articles with "interaction profiling" as a keyword



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Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1

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Published in 2019 at "Oncogene"

DOI: 10.1038/s41388-019-0824-4

Abstract: Fra-1, a member of the activator protein 1 (AP-1) family, is overexpressed in triple-negative breast cancer (TNBC) and plays crucial roles in tumor growth. Here we report the identification of 118 proteins interacting with endogenous… read more here.

Keywords: interaction profiling; identifies ddx5; profiling identifies; ddx5 oncogenic ... See more keywords