Articles with "interactions 90001" as a keyword



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Assessment of drug-drug interactions of CC-90001, a potent and selective inhibitor of c-Jun N-terminal kinase

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Published in 2022 at "Xenobiotica"

DOI: 10.1080/00498254.2022.2027553

Abstract: Abstract CC-90001 is predominantly metabolised via glucuronidation, while oxidative metabolism is a minor pathway in human hepatocytes and liver microsomes. In vitro, CC-90001 glucuronidation was catalysed by UGT1A9, UGT1A4, and UGT1A1, while oxidative metabolism was… read more here.

Keywords: drug drug; drug; inhibitor; interactions 90001 ... See more keywords