Inter-residue interactions in alpha-helical transmembrane proteins
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DOI: 10.1093/bioinformatics/bty978
Abstract: Motivation The number of available membrane protein structures has markedly increased in the last years and, in parallel, the reliability of the methods to detect transmembrane (TM) segments. In the present report, we characterized inter-residue… read more here.
Keywords: transmembrane; membrane proteins; residue interactions; inter residue ... See more keywords
Multivalency drives interactions of alpha-synuclein fibrils with tau
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DOI: 10.1371/journal.pone.0309416
Abstract: Age-related neurodegenerative disorders like Alzheimer’s disease (AD) and Parkinson’s disease (PD) are characterized by deposits of protein aggregates, or amyloid, in various regions of the brain. Historically, aggregation of a single protein was observed to… read more here.
Keywords: multivalency drives; tau; interactions alpha; aggregation ... See more keywords