The Structures of Heterogeneous Membranes and Their Interactions with an Anticancer Peptide: A Molecular Dynamics Study
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12101473
Abstract: We conduct molecular dynamics simulations of model heterogeneous membranes and their interactions with a 24-amino acid peptide—NAF-144–67. NAF-144–67 is an anticancer peptide that selectively permeates and kills malignant cells; it does not permeate normal cells.… read more here.
Keywords: heterogeneous membranes; molecular dynamics; anticancer peptide; interactions anticancer ... See more keywords
Thermodynamic Evaluation of the Interactions between Anticancer Pt(II) Complexes and Model Proteins
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26082376
Abstract: In this work, we have analysed the binding of the Pt(II) complexes ([PtCl(4′-phenyl-2,2′:6′,2″-terpyridine)](CF3SO3) (1), [PtI(4′-phenyl-2,2′:6′,2″-terpyridine)](CF3SO3) (2) and [PtCl(1,3-di(2-pyridyl)benzene) (3)] with selected model proteins (hen egg-white lysozyme, HEWL, and ribonuclease A, RNase A). Platinum coordination compounds… read more here.
Keywords: model proteins; thermodynamic evaluation; anticancer complexes; binding mode ... See more keywords