Abstract 5237: Optimizing multiple myeloma treatment approaches by elucidating tumor-stroma interactions in the bone marrow microenvironment
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DOI: 10.1158/1538-7445.am2025-5237
Abstract: Multiple Myeloma (MM) is a plasma cell malignancy arising in the bone marrow. Despite advancements in therapies, this disease becomes refractory such that relapse and death is inevitable. Immune evasion and drug resistance are partly… read more here.
Keywords: multiple myeloma; interactions bone; cell; marrow microenvironment ... See more keywords
Cell interactions in the bone marrow microenvironment affecting myeloid malignancies.
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DOI: 10.1182/bloodadvances.2020002127
Abstract: The bone marrow is a complex tissue in which heterogeneous populations of stromal cells interact with hematopoietic cells to dynamically respond to organismal needs in defense, hemostasis, and oxygen delivery. Physiologic challenges modify stromal/hematopoietic cell… read more here.
Keywords: cell interactions; microenvironment affecting; interactions bone; marrow microenvironment ... See more keywords