Computational Modeling of the Hsp90 Interactions with Cochaperones and Small-Molecule Inhibitors.
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DOI: 10.1007/978-1-4939-7477-1_19
Abstract: Allosteric interactions of the molecular chaperone Hsp90 with a diverse array of cochaperones and client proteins, such as protein kinases and transcription factors, allow for efficient molecular communication in signal transduction networks. Deregulation of pathways… read more here.
Keywords: computational modeling; modeling hsp90; biology; hsp90 interactions ... See more keywords