Biomolecular Interactions of Cytotoxic Ruthenium Compounds with Thiosemicarbazone or Benzothiazole Schiff Base Chelates
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DOI: 10.1002/cmdc.202200444
Abstract: Herein we illustrate the formation and characterization of new paramagnetic ruthenium compounds, trans‐P‐[RuCl(PPh3)2(pmt)]Cl (1) (Hpmt=1‐((pyridin‐2‐yl)methylene)thiosemicarbazide), trans‐P‐[RuCl(PPh3)2(tmc)]Cl (2) (Htmc=1‐((thiophen‐2‐yl)methylene)thiosemicarbazide) and a diamagnetic ruthenium complex, cis‐Cl, trans‐P‐[RuCl2(PPh3)2(btm)] (3) (btm=2‐((5‐hydroxypentylimino)methyl)benzothiazole). Agarose gel electrophoresis experiments of the metal compounds… read more here.
Keywords: biomolecular interactions; interactions cytotoxic; ruthenium compounds; ruthenium ... See more keywords