Multivalent Interactions with Fbw7 and Pin1 Facilitate Recognition of c-Jun by the SCFFbw7 Ubiquitin Ligase.
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DOI: 10.1016/j.str.2017.11.003
Abstract: Many regulatory proteins, including the transcription factor c-Jun, are highly enriched in disordered protein regions that govern growth, division, survival, differentiation, and response to signals. The stability of c-Jun is controlled by poorly understood regulatory… read more here.
Keywords: jun; ubiquitin ligase; interactions fbw7; multivalent interactions ... See more keywords