Application of an in silico approach identifies a genetic locus within ITGB2, and its interactions with HSPG2 and FGF9, to be associated with anterior cruciate ligament rupture risk.
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DOI: 10.1080/17461391.2023.2171906
Abstract: We developed a Biomedical Knowledge Graph model that is phenotype and biological function-aware through integrating knowledge from multiple domains in a Neo4j, graph database. All known human genes were assessed through the model to identify… read more here.
Keywords: interactions hspg2; cruciate ligament; silico approach; risk ... See more keywords