The interactions of novel mononuclear platinum-based complexes with DNA
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DOI: 10.1186/s12885-018-5194-8
Abstract: BackgroundCisplatin has been widely used for the treatment of cancer and its antitumour activity is attributed to its capacity to form DNA adducts, predominantly at guanine residues, which impede cellular processes such as DNA replication… read more here.
Keywords: novel mononuclear; platinum based; dna; sequence specificity ... See more keywords
Glycan-Lectin Interactions as Novel Immunosuppression Drivers in Glioblastoma
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DOI: 10.3390/ijms23116312
Abstract: Despite diagnostic and therapeutic improvements, glioblastoma (GB) remains one of the most threatening brain tumor in adults, underlining the urgent need of new therapeutic targets. Lectins are glycan-binding proteins that regulate several biological processes through… read more here.
Keywords: interactions novel; novel immunosuppression; glycan lectin; immunosuppression drivers ... See more keywords
Copper-Fructose Interactions: A Novel Mechanism in the Pathogenesis of NAFLD
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DOI: 10.3390/nu10111815
Abstract: Compelling epidemiologic data support the critical role of dietary fructose in the epidemic of obesity, metabolic syndrome and nonalcoholic fatty liver disease (NAFLD). The metabolic effects of fructose on the development of metabolic syndrome and… read more here.
Keywords: copper fructose; copper; high fructose; metabolic syndrome ... See more keywords