Protein-protein interactions: a structural view of inhibition strategies and the IL-23/IL-17 axis.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in protein chemistry and structural biology"
DOI: 10.1016/bs.apcsb.2019.12.006
Abstract: Protein-protein interactions are central to biology and provide opportunities to modulate disease with small-molecule or protein therapeutics. Recent developments in the understanding of the tractability of protein-protein interactions are discussed with a focus on the… read more here.
Keywords: protein; protein interaction; protein interactions; interactions structural ... See more keywords
Interactions, structural aspects, and evolutionary perspectives of the yeast 'START'-regulatory network.
Sign Up to like & getrecommendations! Published in 2021 at "FEMS yeast research"
DOI: 10.1093/femsyr/foab064
Abstract: Molecular signal transduction networks which conduct transcription at the G1 to S phase transition of the eukaryotic cell division cycle have been identified in diverse taxa from mammals to baker´s yeast with analogous functional organization.… read more here.
Keywords: aspects evolutionary; interactions structural; structural aspects; regulatory network ... See more keywords
Polyphilic Interactions as Structural Driving Force Investigated by Molecular Dynamics Simulation (Project 7)
Sign Up to like & getrecommendations! Published in 2017 at "Polymers"
DOI: 10.3390/polym9090445
Abstract: We investigated the effect of fluorinated molecules on dipalmitoylphosphatidylcholine (DPPC) bilayers by force-field molecular dynamics simulations. In the first step, we developed all-atom force-field parameters for additive molecules in membranes to enable an accurate description… read more here.
Keywords: force field; molecular dynamics; interactions structural; polyphilic interactions ... See more keywords