Force-Dependent Interactions between Talin and Full-Length Vinculin.
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DOI: 10.1021/jacs.1c06223
Abstract: Talin and vinculin are part of a multicomponent system involved in mechanosensing in cell-matrix adhesions. Both exist in autoinhibited forms, and activation of vinculin requires binding to mechanically activated talin, yet how forces affect talin's… read more here.
Keywords: vinculin; force; dependent interactions; interactions talin ... See more keywords