Articles with "interactions tumor" as a keyword



Roles and interactions of tumor microenvironment components in medulloblastoma with implications for novel therapeutics

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Published in 2024 at "Genes"

DOI: 10.1002/gcc.23233

Abstract: Medulloblastomas, the most common malignant pediatric brain tumors, can be classified into the wingless, sonic hedgehog (SHH), group 3, and group 4 subgroups. Among them, the SHH subgroup with the TP53 mutation and group 3… read more here.

Keywords: components medulloblastoma; microenvironment components; tumor microenvironment; medulloblastoma implications ... See more keywords

Unveiling Interactions of Tumor-Targeting Nanoparticles with Lipid Bilayers Using a Titratable Martini Model.

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Published in 2024 at "Journal of chemical theory and computation"

DOI: 10.1021/acs.jctc.4c00231

Abstract: pH-responsive nanoparticles are ideal vehicles for drug delivery and are widely used in cell imaging in targeted therapy of cancer, which usually has a weakly acidic microenvironment. In this work, we constructed a titratable molecular… read more here.

Keywords: nanoparticles lipid; lipid bilayer; model; tumor targeting ... See more keywords

A 3D Platform to Investigate Dynamic Cell-to-Cell Interactions Between Tumor Cells and Mesenchymal Progenitors

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Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.767253

Abstract: We here investigated the dynamic cell-to-cell interactions between tumor and mesenchymal stromal/stem cells (MSCs) by the novel VITVOⓇ 3D bioreactor that was customized to develop in vivo-like metastatic nodules of Ewing’s sarcoma (ES). MSCs are… read more here.

Keywords: tumor; cell interactions; interactions tumor; cell ... See more keywords

Cellular Interactions in the Tumor Microenvironment: The Role of Secretome

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Published in 2019 at "Journal of Cancer"

DOI: 10.7150/jca.21780

Abstract: Over the past years, it has become evident that cancer initiation and progression depends on several components of the tumor microenvironment, including inflammatory and immune cells, fibroblasts, endothelial cells, adipocytes, and extracellular matrix. These components… read more here.

Keywords: interactions tumor; tumor microenvironment; cancer; cellular interactions ... See more keywords