Chromatin Immunoprecipitation Assay to Analyze the Effect of G-Quadruplex Interactive Agents on the Binding of RNA Polymerase II and Transcription Factors to a Target Promoter Region.
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DOI: 10.1007/978-1-4939-9666-7_13
Abstract: Growing evidence suggests the existence of G-quadruplexes and their involvement in transcriptional regulation of many human genes, including VEGF. These studies also provide strong evidence that G-quadruplex structures are stabilized by binding to small molecules,… read more here.
Keywords: promoter region; transcription; interactive agents; quadruplex interactive ... See more keywords