The MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase
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DOI: 10.1093/nar/gkac138
Abstract: Abstract Despite MYC dysregulation in most human cancers, strategies to target this potent oncogenic driver remain an urgent unmet need. Recent evidence shows the PP1 phosphatase and its regulatory subunit PNUTS control MYC phosphorylation, chromatin… read more here.
Keywords: myc oncoprotein; myc; interacts chromatin; directly interacts ... See more keywords