An atypical LIR motif within UBA5 (ubiquitin like modifier activating enzyme 5) interacts with GABARAP proteins and mediates membrane localization of UBA5
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DOI: 10.1080/15548627.2019.1606637
Abstract: ABSTRACT Short linear motifs, known as LC3-interacting regions (LIRs), interact with mactoautophagy/autophagy modifiers (Atg8/LC3/GABARAP proteins) via a conserved universal mechanism. Typically, this includes the occupancy of 2 hydrophobic pockets on the surface of Atg8-family proteins… read more here.
Keywords: lir; ubiquitin like; interacts gabarap; gabarap proteins ... See more keywords