AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop
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DOI: 10.1093/nar/gkaa496
Abstract: Abstract Base excision repair (BER) maintains genomic stability through the repair of DNA damage. Within BER, AP-endonuclease 1 (APE1) is a multifunctional enzyme that processes DNA intermediates through its backbone cleavage activity. To accomplish these… read more here.
Keywords: endonuclease; intercalating loop; tyrosine residue; dna ... See more keywords