Intercellular competition and the inevitability of multicellular aging
Sign Up to like & getrecommendations! Published in 2017 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1618854114
Abstract: Significance We lay out the first general model of the interplay between intercellular competition, aging, and cancer. Our model shows that aging is a fundamental feature of multicellular life. Current understanding of the evolution of… read more here.
Keywords: inevitability multicellular; selection; competition; intercellular competition ... See more keywords
Extending the Lifespan of Multicellular Organisms via Periodic and Stochastic Intercellular Competition.
Sign Up to like & getrecommendations! Published in 2022 at "Physical review letters"
DOI: 10.1103/physrevlett.128.218101
Abstract: Resolution of the intrinsic conflict between the reproduction of single cells and the homeostasis of a multicellular organism is central to animal biology and has direct impact on aging and cancer. Intercellular competition is indispensable… read more here.
Keywords: extending lifespan; multicellular organisms; lifespan multicellular; intercellular competition ... See more keywords