Intercellular coupling between peripheral circadian oscillators by TGF-β signaling
Sign Up to like & getrecommendations! Published in 2021 at "Science Advances"
DOI: 10.1126/sciadv.abg5174
Abstract: Paracrine TGF-β signaling is crucial to maintain robust and coherent circadian rhythms of peripheral oscillator networks. Coupling between cell-autonomous circadian oscillators is crucial to prevent desynchronization of cellular networks and disruption of circadian tissue functions.… read more here.
Keywords: coupling peripheral; circadian oscillators; oscillators tgf; intercellular coupling ... See more keywords
Coupling and heterogeneity modulate pacemaking capability in healthy and diseased two-dimensional sinoatrial node tissue models
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Computational Biology"
DOI: 10.1371/journal.pcbi.1010098
Abstract: Both experimental and modeling studies have attempted to determine mechanisms by which a small anatomical region, such as the sinoatrial node (SAN), can robustly drive electrical conduction in the human heart. However, despite important advances… read more here.
Keywords: heterogeneity; sinoatrial node; coupling heterogeneity; intercellular coupling ... See more keywords