Articles with "intercellular crispr" as a keyword



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Computational Discovery of Cancer Immunotherapy Targets by Intercellular CRISPR Screens

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.884561

Abstract: Cancer immunotherapy targets the interplay between immune and cancer cells. In particular, interactions between cytotoxic T lymphocytes (CTLs) and cancer cells, such as PD-1 (PDCD1) binding PD-L1 (CD274), are crucial for cancer cell clearance. However,… read more here.

Keywords: cell; crispr screens; intercellular crispr; immunotherapy targets ... See more keywords