One-step visualization of natural cell activities in non-labeled living spheroids
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-05347-z
Abstract: 3D cultured cell aggregates, including spheroids, reflect the gene expression patterns of living tissues/organs. Mass preparation of spheroids enables high-throughput drug screening (HTS). However, conventional optical imaging of spheroids makes it difficult to obtain sufficient… read more here.
Keywords: intercellular space; visualization; drug; cell ... See more keywords
Understanding Multicellularity: The Functional Organization of the Intercellular Space
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.01170
Abstract: The aim of this paper is to provide a theoretical framework to understand how multicellular systems realize functionally integrated physiological entities by organizing their intercellular space. From a perspective centered on physiology and integration, biological… read more here.
Keywords: space; multicellularity; biological systems; intercellular space ... See more keywords