Network-based method for regions with statistically frequent interchromosomal interactions at single-cell resolution
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DOI: 10.1186/s12859-020-03689-x
Abstract: Background Chromosome conformation capture-based methods, especially Hi-C, enable scientists to detect genome-wide chromatin interactions and study the spatial organization of chromatin, which plays important roles in gene expression regulation, DNA replication and repair etc. Thus,… read more here.
Keywords: single cell; interactions single; cell resolution; interchromosomal interactions ... See more keywords