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Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00255
Abstract: Peptides mediate the interdomain communication of Pin1 (peptidyl-prolyl cis-trans isomerase) and can regulate its conformation and biochemical functions, providing an idea for drug design using Pin1. Two template peptide sequences have been widely used in…
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Keywords:
pser thr;
pin1;
thr pro;
specific pser ... See more keywords
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0
Published in 2020 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.0c00418
Abstract: Sarcolipin (SLN) mediates Ca2+ transport and metabolism in muscle by regulating the activity of the Ca2+ pump SERCA. SLN has a conserved luminal C-terminal domain that contributes to the its functional divergence among homologous SERCA…
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Keywords:
luminal terminal;
communication;
conserved luminal;
sln ... See more keywords