Comparison of Protein Particle Formation in IgG1 mAbs Formulated with PS20 Vs. PS80 When Subjected to Interfacial Dilatational Stress
Sign Up to like & getrecommendations! Published in 2023 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-023-02561-4
Abstract: Polysorbates (PS) are nonionic surfactants that are commonly included in protein formulations to mitigate the formation of interfacial stress-induced protein particles and thus increase their long-term storage stability. Nonetheless, factors that dictate the efficiency of… read more here.
Keywords: stress; particle formation; interfacial dilatational; protein particle ... See more keywords
Effect of Surfactant Molecular Structure on Emulsion Stability Investigated by Interfacial Dilatational Rheology
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DOI: 10.3390/polym13071127
Abstract: Polyglycerol polyricinolate (PGPR) and polyglycerol-2 dioleate were selected as model surfactants to construct water-in-oil (W/O) emulsions, and the effect of interfacial rheological properties of surfactant film on the stability of emulsions were investigated based on… read more here.
Keywords: chain; rheology; interfacial dilatational; structure ... See more keywords