Vitamin D supplementation and serum neurofilament light chain in interferon‐beta‐1b‐treated MS patients
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DOI: 10.1002/brb3.1772
Abstract: Serum neurofilament light chain (sNfL) is a promising biomarker of MS activity, progression, and treatment response. The aim of the present study was to address whether sNfL concentrations are affected by supplementation of vitamin D… read more here.
Keywords: interferon beta; serum neurofilament; neurofilament light; light chain ... See more keywords
Efficacy and safety of favipiravir plus interferon‐beta versus lopinavir/ritonavir plus interferon‐beta in moderately ill patients with COVID‐19: A randomized clinical trial
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27724
Abstract: Favipiravir (FVP), lopinavir/ritonavir (LPV/RTV), and interferon‐beta (INF‐beta) are considered as potential treatments for COVID‐19. We examined the efficacy and safety of FVP and INF‐beta compared to LPV/RTV and INF‐beta combinations for the treatment of SARS‐CoV‐2.… read more here.
Keywords: plus interferon; lpv rtv; interferon beta; beta ... See more keywords
Sphingosine-1-phosphate receptor modulators versus interferon beta for the treatment of relapsing–remitting multiple sclerosis: findings from randomized controlled trials
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DOI: 10.1007/s10072-022-05988-y
Abstract: As one kind of disease-modifying therapies, sphingosine-1-phosphate receptor (S1PR) modulators such as fingolimod, ozanimod, and siponimod have been approved or are being developed to treat multiple sclerosis (MS). Several randomized controlled trials (RCT) have been… read more here.
Keywords: controlled trials; s1pr modulators; interferon beta; beta ... See more keywords
Production of biologically active feline interferon beta in insect larvae using a recombinant baculovirus
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DOI: 10.1007/s13205-018-1369-x
Abstract: Feline interferon beta is a cytokine that belongs to the type I IFN family, with antitumor, antiviral and immunomodulatory functions. In this work, recombinant feline interferon beta (rFeIFNβ) was expressed in insect larvae that constitute… read more here.
Keywords: interferon beta; rfeifn; larvae; feline interferon ... See more keywords
Assessing the Metabolomic Profile of Multiple Sclerosis Patients Treated with Interferon Beta 1a by 1H-NMR Spectroscopy
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DOI: 10.1007/s13311-019-00721-8
Abstract: Metabolomic research has emerged as a promising approach to identify potential biomarkers in multiple sclerosis (MS). The aim of the present study was to determine the effect of interferon beta (IFN ß) on the metabolome… read more here.
Keywords: interferon beta; multiple sclerosis; spectroscopy; assessing metabolomic ... See more keywords
Deciphering the Biophysical Effects of Oxidizing Sulfur-Containing Amino Acids in Interferon-beta-1a using MS and HDX-MS
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DOI: 10.1007/s13361-016-1585-8
Abstract: AbstractIntroduction of a chemical change to one or more amino acids in a protein’s polypeptide chain can result in various effects on its higher-order structure (HOS) and biophysical behavior (or properties). These effects range from… read more here.
Keywords: amino acids; oxidation; interferon beta; sulfur containing ... See more keywords
Specific protein-protein interactions limit the cutaneous iontophoretic transport of interferon beta-1B and a poly-ARG interferon beta-1B analogue.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119913
Abstract: The first objective was to investigate the transdermal iontophoresis of interferon beta 1b (IFN); the second was to determine whether the addition of 10 Arg residues at the N-terminus, creating a highly charged poly-Arg analogue… read more here.
Keywords: interferon beta; delivery; arg; ifn ... See more keywords
Comparing the outcomes of treatment with INF-β 1-a (interferon beta-1a) and IFN-β 1-b (interferon beta-1b) among COVID-19 inpatients
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DOI: 10.1016/j.intimp.2021.108241
Abstract: Background IFNβs are known as one of the most promising drugs used for COVID-19 treatment. This study aimed to investigate the effects of treatment with INF-β 1-a (interferon beta-1a) and IFN-β 1-b (interferon beta-1b) on… read more here.
Keywords: interferon beta; treatment; interferon; ifn recipients ... See more keywords
Chitinase 3-like 1 is associated with the response to interferon-beta treatment in multiple sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2016.12.006
Abstract: Chitinase 3-like 1 (CHI3L1) plays a prognostic role in patients with multiple sclerosis (MS). Here, we investigated a potential association between CHI3L1 and the response to interferon-beta (IFNβ) and glatiramer acetate (GA). Serum CHI3L1 levels… read more here.
Keywords: chitinase like; response; interferon beta; chi3l1 ... See more keywords
Efficacy and safety of interferon beta-1a for intramuscular injections biosimilar in patients with relapsing remitting multiple sclerosis
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DOI: 10.1016/j.jns.2017.08.3473
Abstract: periependymal or diencephalic region, the areas considered as hallmarks of anti-AQP4 antibody positive-NMOSD brain lesions. Only one out of the four cases had prior infection, and the patients tended to relapse without induction of maintenance… read more here.
Keywords: injections biosimilar; beta intramuscular; efficacy safety; interferon beta ... See more keywords
BVDV-1 induces interferon-beta gene expression through a pathway involving IRF1, IRF7, and NF-κB activation.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular immunology"
DOI: 10.1016/j.molimm.2020.09.018
Abstract: The bovine viral diarrhea virus (BVDV-1) is a pathogen with the capacity to modulate the interferon type I system. To further investigate the effects of BVDV-1 on the production of the immune response, the Madin-Darby… read more here.
Keywords: interferon beta; bvdv induces; induces interferon; expression ... See more keywords