Hepatitis C Virus and Interferon-Free Antiviral Therapeutics Revolution: Implications for Pakistan.
Sign Up to like & getrecommendations! Published in 2017 at "Viral Immunology"
DOI: 10.1089/vim.2016.0164
Abstract: Abstract Hepatitis C virus (HCV) is a major health concern worldwide as a leading cause of liver-related mortalities and morbidities. Pakistan ranks second among countries with endemic HCV infection; ∼11 million cases are reported so… read more here.
Keywords: virus interferon; interferon free; hepatitis; free antiviral ... See more keywords
Interferon-Free Hepatitis C Virus Therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a036855
Abstract: Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with ∼71 million chronically infected individuals worldwide. Treatment of patients with HCV-related liver disease has advanced considerably thanks to the development of… read more here.
Keywords: virus therapy; interferon free; hepatitis; hepatitis virus ... See more keywords
Hepatitis C treatment from “response‐guided” to “resource‐guided” therapy in the transition era from interferon‐containing to interferon‐free regimens
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.13747
Abstract: Peginterferon/ribavirin has been the standard‐of‐care for chronic hepatitis C virus (HCV) infections: 48 weeks for genotype 1 or 4 (HCV‐1/4) and 24 weeks for HCV‐2/3. Response‐guided therapy recommended shorter 24‐ and 16‐week regimens for HCV‐1… read more here.
Keywords: free regimens; interferon free; interferon containing; response ... See more keywords
Uptake of interferon‐free DAA therapy among HCV‐infected decompensated cirrhosis patients and evidence for decreased mortality
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DOI: 10.1111/jvh.13543
Abstract: Interferon‐free DAA therapies have recently been licensed for patients infected with hepatitis C virus (HCV) who have decompensated cirrhosis (DC). Our aim was to describe factors associated with uptake of IFN‐free DAAs in DC patients… read more here.
Keywords: interferon free; daa; daa era; mortality ... See more keywords
Diabetes Mellitus Prevents an Improvement in the Serum Albumin Level During Interferon-free Sofosbuvir-based Therapy for Chronic Hepatitis C Patients: A Multi-institutional Joint Study
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DOI: 10.2169/internalmedicine.9857-17
Abstract: Objective Interferon-free regimens of direct-acting antiviral agents have improved the treatment response for chronic hepatitis C virus (HCV) infection, and improvement in the serum albumin level during interferon-free therapy has been reported. The aim of… read more here.
Keywords: interferon free; albumin level; serum albumin;
All Oral Interferon-free Direct-acting Antivirals as Combination Therapies to Cure Hepatitis C.
Sign Up to like & getrecommendations! Published in 2018 at "Current molecular medicine"
DOI: 10.2174/1566524019666190104110439
Abstract: Chronic hepatitis C (CHC) virus infection and associated hepatic diseases are still challenging, and the disease burden remains significant around the world. Overall treatment rates for the chronically infected patients have been "dismally poor" and… read more here.
Keywords: interferon free; treatment; hcv; direct acting ... See more keywords
Liver transplantation from HCV RNA-positive donors in the era of interferon-free HCV therapeutics: a re-examination of the situation.
Sign Up to like & getrecommendations! Published in 2017 at "Minerva gastroenterologica e dietologica"
DOI: 10.23736/s1121-421x.16.02347-3
Abstract: Although the availability of donor organs is limited, liver grafts from HCV-positive donors remained yet an obstacle, primarily because of limited therapeutic options for HCV reinfection and lower rates of graft and patient survival. However,… read more here.
Keywords: interferon free; treatment; hcv; liver transplantation ... See more keywords
Efficiency and Tolerability of Interferon Free Therapy - Positive Impact on the Quality of Life of Patients with Chronic Viral Hepatitis C
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DOI: 10.2478/inmed-2023-0234
Abstract: Abstract Introduction. The infection with hepatitis C (HCV) is a major cause of chronic liver diseases, with approximately 71,000.000 chronically infected persons worldwide. Material and methods. This study includes the results of the evaluation of… read more here.
Keywords: patients chronic; interferon free; therapy; quality life ... See more keywords
Impact of interferon-free antivirus therapy on lipid profiles in patients with chronic hepatitis C genotype 1b
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DOI: 10.3748/wjg.v23.i13.2355
Abstract: AIM To investigate the influence of interferon-free antivirus therapy on lipid profiles in chronic hepatitis C virus genotype 1b (HCV1b) infection. METHODS Interferon-free antiviral agents were used to treat 276 patients with chronic HCV1b infection,… read more here.
Keywords: sof ldv; interferon free; lipid profiles; treatment ... See more keywords
Impact of ITPA Gene Polymorphisms on the Risk of Ribavirin-Induced Haemolytic Anaemia using Interferon-Free Antivirals for Chronic Hepatitis C
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DOI: 10.3851/imp3138
Abstract: Background Single nucleotide polymorphisms (SNPs) at the ITPA gene are associated with haemolytic anaemia in chronic hepatitis C patients treated with pegylated interferon-ribavirin (RBV). Information in patients treated with interferon-free, direct-acting antivirals (DAA) is scarce.… read more here.
Keywords: interferon free; itpa gene; hepatitis; chronic hepatitis ... See more keywords