Enhanced Prevention of Breast Tumor Metastasis by Nanoparticle-Delivered Vitamin E in Combination with Interferon-Gamma.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201901706
Abstract: Preventing cancer metastasis is one of the remaining challenges in cancer therapy. As an efficient natural product, alpha-tocopheryl succinate (α-TOS), the most effective form of vitamin E, holds great anticancer potential. To improve its efficacy… read more here.
Keywords: combination; combination interferon; metastasis; interferon gamma ... See more keywords
Glucose–methanol‐based fed‐batch fermentation for the production of recombinant human interferon gamma (rhIFN‐γ) and evaluation of its antitumor potential
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1868
Abstract: Squamous cell carcinoma (SCC) is nonmelanoma skin cancer, which is very common in patients having T‐cell immunosuppressant drugs. Anticancerous agents such as cytokines showed effective response on SCC. Human interferon‐gamma (hIFN‐γ), a type II cytokines,… read more here.
Keywords: rhifn; production; human interferon; interferon gamma ... See more keywords
Production of interferon-gamma, interleukin-6, and interleukin-1β by human peripheral blood mononuclear cells stimulated with novel lys-gingipain synthetic peptides.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of periodontology"
DOI: 10.1002/jper.18-0626
Abstract: BACKGROUND Periodontitis is a progressive inflammatory process, and its pathogenesis is related to the presence of a dysbiotic subgingival biofilm that elicits the immune response. Porphyromonas gingivalis is a keystone pathogen, and its Lys-gingipain (Kgp)… read more here.
Keywords: peripheral blood; lys gingipain; production; synthetic peptides ... See more keywords
Interferon-gamma release assays outcomes in healthy subjects following BNT162b2 mRNA COVID-19 vaccination
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology International"
DOI: 10.1007/s00296-022-05091-7
Abstract: The pathogenesis of COVID-19 involves both humoral and cellular immunological responses, with cell-mediated immunity being discussed as the primary and most effective immune response to viral infection. It is supposed that COVID-19 vaccines also elicited… read more here.
Keywords: sars cov; vaccination; mrna covid; interferon gamma ... See more keywords
Evaluation of interferon gamma (IFN-γ) of Labeo rohita as an immunomodulator: in vitro expression model
Sign Up to like & getrecommendations! Published in 2018 at "Aquaculture International"
DOI: 10.1007/s10499-018-0292-9
Abstract: Interferon gamma (IFN-γ) or type II interferon is a cytokine that is critical for innate and adaptive immunity against viral and some bacterial and protozoal infections. The importance of IFN-γ in the immune system lies… read more here.
Keywords: ifn; expression; interferon gamma; gamma ifn ... See more keywords
IMPACT OF COMORBIDITIES ON THE PERFORMANCE OF INTERFERON GAMMA RELEASE ASSAY IN A GREEK ELDERLY POPULATION WITHOUT OVERT IMMUNODEFICIENCY.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2020.106073
Abstract: Background The prevalence of latent Tuberculosis Infection (LTBI) increases with aging. Interferon gamma release assay (IGRA) is a T-cell based assay, widely used for the detection of LTBI. Objectives To identify the prevalence of LTBI… read more here.
Keywords: release assay; gamma release; interferon gamma; igra ... See more keywords
Indoleamine 2,3-Dioxygenase Activation by Interferon Gamma in Vascular Endothelial Cells Requires Noncanonical NF-κB Signaling.
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2019.03.043
Abstract: Indoleamine 2,3-dioxygenase (IDO) is an important enzyme in immune response regulation; cells that express IDO can suppress T-cell responses. Endothelial cells (ECs) play an important role in graft rejection. Therefore, we investigated the role of… read more here.
Keywords: noncanonical signaling; endothelial cells; activation; interferon gamma ... See more keywords
Targeted Delivery of Interferon Gamma Using a Recombinant Fusion Protein of a Fibrin Clot-Binding Peptide With Interferon Gamma for Cancer Gene Therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2016.11.018
Abstract: Accelerated formation of fibrin clots in a tumor microenvironment can be used for targeted delivery of interferon gamma (IFNγ) to tumor cells. Here, we selected cysteine-arginine-glutamic acid-lysine-alanine (CREKA) as the fibrin clot-binding peptide and designed… read more here.
Keywords: creka; mmp creka; ifn; interferon gamma ... See more keywords
DNA-Based Photoacoustic Nanosensor for Interferon Gamma Detection.
Sign Up to like & getrecommendations! Published in 2019 at "ACS sensors"
DOI: 10.1021/acssensors.9b00209
Abstract: Tracking protein levels in the body is vital in both research and medicine, where understanding their physiological roles provides insight into their regulation in homeostasis and diseases. In medicine, protein levels are actively sampled since… read more here.
Keywords: protein; medicine; dna; interferon ... See more keywords
Detection of Mycobacterium tuberculosis complex infection in Asian elephants (Elephas maximus) using an interferon gamma release assay in a captive elephant herd
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71099-3
Abstract: Tuberculosis is highly contagious disease that can be transmitted between humans and animals. Asian elephants (Elephas maximus) in captivity live in close contact with humans in many Asian countries. In this study, we developed an… read more here.
Keywords: detection; asian elephants; infection; interferon ... See more keywords
Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2115987119
Abstract: Significance Since their discovery over 30 y ago, it has become clear that the superantigens (SAgs) are important virulence factors produced during severe Staphylococcus aureus–mediated disease including bacteremia. However, until the current study, it was… read more here.
Keywords: staphylococcus aureus; infection; aureus; interferon gamma ... See more keywords