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   Articles with "interferon gene" as a keyword



Identification and function analysis of canine stimulator of interferon gene (STING)

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recommendations! Published in 2017 at "Microbial Pathogenesis"

DOI: 10.1016/j.micpath.2017.10.047

Abstract: Abstract Stimulator of interferon gene (STING) plays an important role in the cyclic GMP-AMP synthase (cGAS)-mediated activation of type I IFN responses. In this study, we identified and cloned canine STING gene. Full-length STING encodes… read more here.

Keywords: stimulator interferon; gene sting; canine; interferon gene ... See more keywords

Stimulator of interferon gene facilitates recruitment of effector CD8 T cells that drive neurofibromatosis type 1 nerve tumor initiation and maintenance

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recommendations! Published in 2024 at "Science Advances"

DOI: 10.1126/sciadv.ado6342

Abstract: Plexiform neurofibromas (PNFs) are benign nerve tumors driven by loss of the NF1 tumor suppressor in Schwann cells. PNFs are rich in immune cells, but whether immune cells are necessary for tumorigenesis is unknown. We… read more here.

Keywords: initiation; cd8 cells; tumor; stimulator interferon ... See more keywords

Anti-RNP antibodies are associated with the interferon gene signature but not decreased complement levels in SLE

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recommendations! Published in 2022 at "Annals of the Rheumatic Diseases"

DOI: 10.1136/annrheumdis-2021-221662

Abstract: Objectives The goals of these studies were to elucidate the inter-relationships of specific anti-nuclear antibody (ANA), complement, and the interferon gene signature (IGS) in the pathogenesis of systemic lupus erythematosus (SLE). Methods Data from the… read more here.

Keywords: anti dsdna; gene signature; anti rnp; interferon gene ... See more keywords

Isolation and expression analysis of stimulator of interferon gene from olive flounder, Paralichthys olivaceus

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recommendations! Published in 2018 at "Fisheries and Aquatic Sciences"

DOI: 10.1186/s41240-018-0083-2

Abstract: Stimulator of interferon gene (STING) is induced by various inflammatory agents, such as lipopolysaccharide and microbial pathogens, including virus and bacteria. In this study, we obtained a full-length cDNA of a STING homolog from olive… read more here.

Keywords: stimulator interferon; interferon gene; expression; olive flounder ... See more keywords

Stimulator of Interferon Gene Agonists Induce an Innate Antiviral Response against Influenza Viruses

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recommendations! Published in 2024 at "Viruses"

DOI: 10.3390/v16060855

Abstract: The devastating effects of COVID-19 have highlighted the importance of prophylactic and therapeutic strategies to combat respiratory diseases. Stimulator of interferon gene (STING) is an essential component of the host defense mechanisms against respiratory viral… read more here.

Keywords: influenza; response; stimulator interferon; interferon gene ... See more keywords