Ethnic variation in risk genotypes based on single nucleotide polymorphisms (SNPs) of the interferon-inducible transmembrane 3 (IFITM3) gene, a susceptibility factor for pandemic 2009 H1N1 influenza A virus
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DOI: 10.1007/s00251-020-01188-0
Abstract: The interferon-inducible transmembrane 3 (IFITM3) protein is an effector of the host innate immune system that shows defensive activity against a wide range of viruses, including the influenza A virus. Previous studies have reported that… read more here.
Keywords: interferon inducible; inducible transmembrane; influenza; risk genotypes ... See more keywords
Plasma interferon-γ-inducible protein 10 (IP-10) levels correlate with disease severity and paradoxical reactions in extrapulmonary tuberculosis
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DOI: 10.1007/s15010-020-01541-1
Abstract: With 1.5 million deaths worldwide in 2018, tuberculosis (TB) remains a major global public health problem. While pulmonary TB (PTB) is the most common manifestation, the proportion of extrapulmonary TB (EPTB) is increasing in low-burden… read more here.
Keywords: interferon inducible; disease; inducible protein; tuberculosis ... See more keywords
Interferon-inducible TRIM22 contributes to maintenance of HIV-1 proviral latency in T cell lines.
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DOI: 10.1016/j.virusres.2019.05.009
Abstract: The human immunodeficiency virus type-1 (HIV-1) establishes a state of latent infection in a small number of CD4+ T lymphocytes that, nonetheless, represent a major obstacle to viral eradication. We here show that Tripartite Motif-containing… read more here.
Keywords: latency; interferon inducible; cell lines; hiv ... See more keywords
RNA-Seq analysis of interferon inducible p204-mediated network in anti-tumor immunity
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DOI: 10.1038/s41598-018-24561-2
Abstract: Abstractp204, a murine member of the interferon-inducible p200 protein family, and its human analogue, IFI16, have been shown to function as tumor suppressors in vitro, but the molecular events involved, in particular in vivo, remain… read more here.
Keywords: interferon inducible; p204; anti tumor; p204 mice ... See more keywords
Interferon-inducible protein, IFIX, has tumor-suppressive effects in oral squamous cell carcinoma
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DOI: 10.1038/s41598-021-99157-4
Abstract: IFIX, a newly discovered member of the interferon-inducible HIN-200 family, has been identified as a tumor suppressor in breast cancer; however, the involvement of IFIX in oral cancer are poorly understood. Here, we demonstrate a… read more here.
Keywords: interferon inducible; cell carcinoma; squamous cell; cell ... See more keywords
The expression of Ets-1 and Fli-1 is associated with interferon-inducible genes in peripheral blood mononuclear cells from Japanese patients with systemic lupus erythematosus
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DOI: 10.1097/md.0000000000031522
Abstract: Transcription factors E26 transformation-specific-1 (Ets-1) and Friend leukemia insertion site-1 (Fli-1) and type I interferon (IFN) have been implicated in systemic lupus erythematosus (SLE). We examined the expression of these genes in peripheral blood mononuclear… read more here.
Keywords: ets fli; patients sle; japanese patients; expression ... See more keywords
Retracted: Human Interferon Inducible Transmembrane Protein 3 (IFITM3) Inhibits Influenza Virus A Replication and Inflammation by Interacting with ABHD16A
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DOI: 10.1155/2022/9790782
Abstract: [This retracts the article DOI: 10.1155/2021/6652147.]. read more here.
Keywords: inducible transmembrane; interferon inducible; retracted human; human interferon ... See more keywords
Abstract 1704: Interferon inducible ADAR1 is essential for the survival of oral squamous cell carcinoma
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DOI: 10.1158/1538-7445.am2023-1704
Abstract: Treating oral squamous cell carcinoma (OSCC) remains challenging due to limited knowledge of the critical genes that could affect cell survival in OSCC. We have previously utilized genome-wide CRISPR-Cas9 knockout functional screens to explore the… read more here.
Keywords: cell carcinoma; cell; squamous cell; adar1 ... See more keywords
Interferon inducible pseudouridine modification in human mRNA by quantitative nanopore profiling
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DOI: 10.1186/s13059-021-02557-y
Abstract: Pseudouridine (Ψ) is an abundant mRNA modification in mammalian transcriptome, but its functions have remained elusive due to the difficulty of transcriptome-wide mapping. We develop a nanopore native RNA sequencing method for quantitative Ψ prediction… read more here.
Keywords: pseudouridine modification; interferon inducible; inducible pseudouridine; pseudouridine ... See more keywords
Interferon α-inducible protein 27 is an oncogene and highly expressed in cholangiocarcinoma patients with poor survival
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DOI: 10.2147/cmar.s196485
Abstract: Objective Cholangiocarcinoma (CCA) is a devastating disease. Interferon α-inducible protein 27 (IFI27), originally known to involve in innate immunity, is later found to intervene in cell proliferation, leading to inventive studies regarding the role of… read more here.
Keywords: ifi27 knockdown; interferon inducible; cell; inducible protein ... See more keywords
Overexpression of the Interferon-Inducible Isoform 4 of NCOA7 Dissects the Entry Route of Enveloped Viruses and Demonstrates that HIV Enters Cells via Fusion at the Plasma Membrane
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DOI: 10.3390/v11020121
Abstract: The HIV-1 entry-route is a matter of ongoing controversy, and there is evidence for fusion either at the cell surface or from within endosomes. A recent report demonstrated that isoform 4 of nuclear receptor coactivator… read more here.
Keywords: interferon inducible; entry; fusion; overexpression interferon ... See more keywords